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FGF21-FGFR1 signaling protects against cardiac hypertrophy by regulating PINK1-mediated mitophagy pathway

Introduction: Cardiac hypertrophy is an independent risk factor and the primary predictor of heart failure (HF). Mitochondria are crucial for the shift from hypertrophy to heart failure. The expression of fibroblast growth factor 21 (FGF21), a cardioprotective factor, is increased in patients with c...

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Bibliografische gegevens
Hoofdauteurs: Lei Chen, Lingxin Zheng, Yuan Qin, Bilin Liu, Yejing Zheng, Xiaojian Tong, Mengting Dai, Guohua Gong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2026-07-01
Reeks:Journal of Advanced Research
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Online toegang:http://www.sciencedirect.com/science/article/pii/S2090123225008483
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