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The role of cellular reactive oxygen species in cancer chemotherapy

Abstract Most chemotherapeutics elevate intracellular levels of reactive oxygen species (ROS), and many can alter redox-homeostasis of cancer cells. It is widely accepted that the anticancer effect of these chemotherapeutics is due to the induction of oxidative stress and ROS-mediated cell injury in...

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Hauptverfasser: Haotian Yang, Rehan M Villani, Haolu Wang, Matthew J Simpson, Michael S Roberts, Min Tang, Xiaowen Liang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-11-01
Schriftenreihe:Journal of Experimental & Clinical Cancer Research
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Online-Zugang:http://link.springer.com/article/10.1186/s13046-018-0909-x
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