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IN-VITRO AND IN-VIVO EVALUATION OF SUSTAINED-RELEASE SUPPOSITORIES CONTAINING THEOPHYLLINE MICROSPHERES

The sustained release microspheres of theophylline were formulated using non-solvent addition technique. The in-vitro dissolution of the drug from the fabricated microspheres that having size ranges of 300-600, 600-800 and 800-1000 µm was tested. The release of theophylline was extended over 8 hrs a...

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Principais autores: Gamal Mahrous, Hesham Tawfeek, Sayed Auda, Gamal Shazly
Format: Artigo
Jezik:Inglês
Izdano: Assiut University, Faculty of Pharmacy 2015-12-01
Serija:Bulletin of Pharmaceutical Sciences. Assiut University
Online dostop:https://bpsa.journals.ekb.eg/article_63177_e8dea063f5cc0a2f9ebc61c6c608ab0e.pdf
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