The Cholinergic Receptor Nicotinic α3 Was Reduced in the Hippocampus of Early Cognitively Impaired Adult Male Mice and Upregulated by Nicotine and Cytisine in HT22 Cells

Ageing is a major risk factor for cognitive and physical decline, but its mechanisms remain poorly understood. This study aimed to detect early cognitive and physical changes, and to analyze the pathway involved by monitoring two groups of mice: a young and an adult group. The study has identified t...

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Principais autores:	Hidetaka Ota, Takako Ohnuma, Ayuto Kodama, Tatsunori Shimizu, Kaoru Sugawara, Fumio Yamamoto
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2025-02-01
Serija:	Cells
Teme:	early age-related cognitive decline frailty cholinergic receptor nicotinic ?3 subunit nicotine cytisine
Online dostop:	https://www.mdpi.com/2073-4409/14/5/340
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