Single cell proteomic analysis defines discrete neutrophil functional states in human glioblastoma

Abstract Neutrophils are vital innate immune cells shown to infiltrate glioblastomas, however we currently lack the molecular understanding of their functional states within the tumour niche. Given that neutrophils are known to display a prominent discordance between mRNA and protein abundance, we d...

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Autors principals:	Pranvera Sadiku, Alejandro J. Brenes, Rupert L. Mayer, Leila Reyes, Patricia Coelho, Gabi van Stralen, Ailiang Zhang, Manuel A. Sanchez-Garcia, Emily R. Watts, Imran Liaquat, Andrew J. M. Howden, Ikeoluwa Adekoya, Anuka Boldbaatar, Allan MacRaild, Sarah Risbridger, Gillian M. Morrison, Heather MacPherson, Caroline M. Bruce, Shonna Johnston, Robert Grecian, Fiona A. Murphy, Steven M. Pollard, Paul M. Brennan, Karl Mechtler, Sarah R. Walmsley
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-12-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-025-67367-3
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