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Higher methylation subtype of malignant melanoma and its correlation with thicker progression and worse prognosis

Abstract Malignant melanoma (MM) is the most life‐threatening disease among all skin malignancies, and recent genome‐wide studies reported BRAF, RAS, and NF1 as the most frequently mutated driver genes. While epigenetic aberrations are known to contribute to the oncogenic activity seen in various ca...

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Principais autores: Yosuke Yamamoto, Keisuke Matsusaka, Masaki Fukuyo, Bahityar Rahmutulla, Hiroyuki Matsue, Atsushi Kaneda
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2020-10-01
coleção:Cancer Medicine
Assuntos:
DNA methylation
epigenotype
invasion
malignant melanoma
skin neoplasm
Acesso em linha:https://doi.org/10.1002/cam4.3127
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