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A NIR fluorescent probe for Vanin-1 and its applications in imaging, kidney injury diagnosis, and the development of inhibitor

Vanin-1 is an amidohydrolase that catalyses the conversion of pantetheine into the amino-thiol cysteamine and pantothenic acid (coenzyme A precursor), which plays a vital role in multiple physiological and pathological processes. In this study, an enzyme-activated near-infrared (NIR) fluorescent pro...

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Principais autores: Zhenhao Tian, Fei Yan, Xiangge Tian, Lei Feng, Jingnan Cui, Sa Deng, Baojing Zhang, Tian Xie, Shanshan Huang, Xiaochi Ma
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
coleção:Acta Pharmaceutica Sinica B
Assuntos:
Vanin-1
NIR fluorescent probe
Kidney injury diagnosis
Fluorescence imaging
Oleuropein
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211383521002161
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