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The prognostic significance of JAML and its role in remodeling the immune microenvironment via the cGAS-STING pathway in endometrial cancer

BackgroundEndometrial cancer (EC) is a major gynecological malignancy with a poor prognosis in the advanced stages. Junctional adhesion molecule-like protein (JAML) is gaining attention in cancer biology; however, its role in EC remains unclear.MethodsThis study integrated multi-omics data (TCGA, pa...

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Huvudupphov: Chenfan Tian, Yuanyang Yao, Yuan Tu, Jiaxin Yu, Chunxia Gong, Xiuling Shi, Hangkun Yu, Peng Jiang
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2026-01-01
Serie:Frontiers in Immunology
Ämnen:
chemosensitivity
endometrial carcinoma
immunotherapy
JAML
nomogram model
prognosis
Länkar:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1738596/full
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