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TIE-UP-SIN: A Method for Enhanced Identification of Protein–Protein Interactions

Protein–protein interactions (PPIs) govern nearly all aspects of cellular physiology, yet identifying these interactions under native conditions remains challenging. Here, we present TIE-UP-SIN (targeted interactome experiment for unknown proteins by stable isotope normalization), a robust method fo...

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Auteurs principaux: Maximilian Schedlowski, Stephan Michalik, Tilly Hoffmüller, Marco Harms, Leif Steil, Kristin Surmann, Christian Hentschker, Manuela Salazar, Uwe Völker, Alexander Reder
Format: Artigo
Langue:Inglês
Publié: Bio-protocol LLC 2026-04-01
Collection:Bio-Protocol
Accès en ligne:https://bio-protocol.org/en/bpdetail?id=5663&type=0
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