T-cell activation of Toxoplasma gondii positive donors by maltodextrin nanoparticles formulated with killed Toxoplasma gondii

Abstract Nasal vaccination with killed tachyzoites from Toxoplasma gondii loaded in lipidated maltodextrin nanoparticles (NPL/T.gondii) has been shown to induce protection against lethal T.gondii infection in mice, sheep and squirrel monkeys. This protection was related to a unique T-cell mediated r...

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Auteurs principaux:	Monica Vargas-Montes, François Fasquelle, Nestor Ivan Cardona, Jorge Enrique Gómez-Marín, Didier Betbeder
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2025-02-01
Collection:	BMC Infectious Diseases
Sujets:	PBMC Nanoparticles Toxoplasma gondii Antigen delivery Interferon-gamma Vaccine
Accès en ligne:	https://doi.org/10.1186/s12879-025-10656-5
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