Peroxynitrite promotes serine-62 phosphorylation-dependent stabilization of the oncoprotein c-Myc
Stabilization of c-Myc oncoprotein is dependent on post-translational modifications, especially its phosphorylation at serine-62 (S62), which enhances its tumorigenic potential. Herein we report that increase in intracellular superoxide induces phospho-stabilization and activation of c-Myc in cancer...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020-07-01
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| Schriftenreihe: | Redox Biology |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2213231720303189 |
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