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Decreased Netrin-1 in Mild Cognitive Impairment and Alzheimer’s Disease Patients

Background and ObjectiveInflammatory mediators are closely associated with the pathogenesis of Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Netrin-1 is an axon guidance protein and despite its capacity to function as a neuroimmune guidance signal, its role in AD or MCI is poorly und...

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Principais autores: Ting Ju, Lina Sun, Yuwei Fan, Tianhang Wang, Yanchen Liu, Dan Liu, Tianyi Liu, Chang Zhao, Wenxin Wang, Lijun Chi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-02-01
coleção:Frontiers in Aging Neuroscience
Assuntos:
Alzheimer’s disease
mild cognitive impairment
netrin-1
IL-17
TNF-α
neuroinflammation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnagi.2021.762649/full
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