Mendelian randomization analysis of immune cell subsets and inflammatory cytokines in aplastic anaemia

Abstract Aplastic anemia (AA) is an immune-mediated bone marrow failure syndrome marked by pancytopenia and depletion of hematopoietic stem cells. Although autoreactive T cells and inflammatory cytokines are involved in its pathogenesis, their causal relationships remain unclear. We conducted a bidi...

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Detalles Bibliográficos

Autores principales:	Keyue Hu, Yiquan Cheng, Gangfeng Xiao, Xiu Shen, Jingwen Zhu, Mengmeng Huang, Yang Fei, Suying Qian, Xiaona Shao
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Springer 2026-01-01
Colección:	Annals of Hematology
Materias:	Immune cells Inflammatory cytokines Leukemia inhibitory factor Aplastic anemia Mendelian randomization Mediation analysis
Acceso en línea:	https://doi.org/10.1007/s00277-026-06759-x
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