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Hydrogen-bond driven loop-closure kinetics in unfolded polypeptide chains.

Characterization of the length dependence of end-to-end loop-closure kinetics in unfolded polypeptide chains provides an understanding of early steps in protein folding. Here, loop-closure in poly-glycine-serine peptides is investigated by combining single-molecule fluorescence spectroscopy with mol...

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Hlavní autoři: Isabella Daidone, Hannes Neuweiler, Sören Doose, Markus Sauer, Jeremy C Smith
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2010-01-01
Edice:PLoS Computational Biology
On-line přístup:http://europepmc.org/articles/PMC2799665?pdf=render
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