Caspase cleavage of influenza A virus M2 disrupts M2-LC3 interaction and regulates virion production
Abstract Influenza A virus (IAV) Matrix 2 protein (M2) is an ion channel, required for efficient viral entry and egress. M2 interacts with the small ubiquitin-like LC3 protein through a cytoplasmic C-terminal LC3-interacting region (LIR). Here, we report that M2 is cleaved by caspases, abolishing th...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer Nature
2025-03-01
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| Seri Bilgileri: | EMBO Reports |
| Konular: | |
| Online Erişim: | https://doi.org/10.1038/s44319-025-00388-7 |
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