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Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells

Human immunodeficiency virus type-1 (HIV-1) elite controllers (ELCs) represent a unique population that control viral replication in the absence of antiretroviral therapy (cART). It is well established that expression of multiple inhibitory receptors on CD8+ T cells is associated with HIV-1 disease...

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Hoofdauteurs: Kajsa Noyan, Son Nguyen, Michael R. Betts, Anders Sönnerborg, Marcus Buggert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018-01-01
Reeks:Frontiers in Immunology
Onderwerpen:
human immunodeficiency virus type-1
elite controllers
CD4+ T cells
T cell exhaustion
inhibitory receptors
programmed cell death-1
Online toegang:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00019/full
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