Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice

Myelodysplastic syndrome (MDS) is a heterogeneous group of bone marrow stem cell disorders characterized by ineffective hematopoiesis and cytopenias, most commonly anemia. Red cell transfusion therapy for anemia in MDS results in iron overload, correlating with reduced overall survival. Whether the...

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Principais autores:	Wenbin An, Maria Feola, Maayan Levy, Srinivas Aluri, Marc Ruiz-Martinez, Ashwin Sridharan, Eitan Fibach, Xiaofan Zhu, Amit Verma, Yelena Ginzburg
Formato:	Artigo
Idioma:	Inglês
Publicado:	eLife Sciences Publications Ltd 2023-12-01
Series:	eLife
Assuntos:	myelodysplastic dyndrome deferiprone ineffective erythropoiesis iron trafficking
Acceso en liña:	https://elifesciences.org/articles/83103
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