Cardiorespiratory fitness does not predict longitudinal changes in manual dexterity, cognition or corticospinal excitability in multiple sclerosis

IntroductionNeurodegeneration in multiple sclerosis leads to progressive cognitive and motor impairments. Cardiorespiratory fitness (CRF) is thought to protect against such decline, but its longitudinal effects remain unclear. This study examined whether CRF predicts changes in behavioral (i.e., han...

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Autors principals:	Basel Mohamed, Sarah Duraid, Nick W. Bray, Arthur R. Chaves, Michelle Ploughman
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-01-01
Col·lecció:	Frontiers in Aging Neuroscience
Matèries:	neurodegeneration cardiorespiratory fitness manual hand dexterity global cognition transcranial magnetic stimulation neurological disorder
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnagi.2025.1628832/full
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