Incidence and predictors of vancomycin nephrotoxicity and mortality in patients with chronic liver disease: a two-center retrospective cohort study

Abstract Background Patients with liver disease express multiple pathophysiological variations that alter the pharmacokinetics of numerous drugs. At this time, there is insufficient evidence about the proper dosing of vancomycin in patients with liver disease. This study aimed to assess the risk of...

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Autori principali:	Reem F. Bamogaddam, Ahmad Alamer, Shatha Alqarni, Mohammed M. Almotairi, Ali A. Almakrami, Alwaleed M. Alharbi, Raghad Alamri, Manar Altamimi, Amal Alkhulaif, Raghad Alanazi, Omar A. Almohammed, Majed S. Al Yami
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-03-01
Serie:	BMC Infectious Diseases
Soggetti:	Vancomycin Vancomycin trough level Toxicity Liver disease Creatinine clearance Acute kidney injury
Accesso online:	https://doi.org/10.1186/s12879-025-10763-3
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