DMSO might impact ligand binding, capsid stability, and RNA interaction in viral preparations
Abstract Dimethyl sulfoxide (DMSO) is a widely used solvent in drug research. However, recent studies indicate that even at low concentration DMSO might cause structural changes of proteins and RNA. The pyrazolopyrimidine antiviral OBR-5-340 dissolved in DMSO inhibits rhinovirus-B5 infection yet is...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Portfolio
2024-12-01
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| Sarja: | Scientific Reports |
| Aiheet: | |
| Linkit: | https://doi.org/10.1038/s41598-024-81789-x |
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