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In silico reconstructions underpin aberrant trafficking dynamics in deficient axons of Dst knockout and Dst/Nefl double-knockout mice

Abstract Aberrant neuronal trafficking is a significant hallmark of neurodegenerative pathology. Its real-time evolution remains elusive and poorly defined due to the lack of a predictive spatiotemporal framework. Building upon a general neurocytoskeletal-PDEs (iGCPs) model, we propose the concept o...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Zongmin Liu, Wei Wang, Elena Zhang, Emanuel Manzo-Casio, Audrey Liu, Annabelle Yao, Jianqing Ding, Yanmin Yang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2025-09-01
Rangatū:Communications Biology
Urunga tuihono:https://doi.org/10.1038/s42003-025-08728-y
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