Reducing Functional Domain of Histatin 5 Improves Antifungal Activity and Prevents Proteolytic Degradation

Histatin 5 (Hst5) is an antifungal peptide (AFP) naturally produced by parotid glands with strong activity against <i>Candida albicans</i>. One of its mechanisms of action is the generation of reactive oxygen species (ROS) inside the <i>C. albicans</i> cells. Despite being an important peptide for t...

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Principais autores:	Carolina R. Zambom, Gabriel Bernardes, Fauller Henrique da Fonseca, Gabriela Vieira Silva Zolin, Mariana de Melo Faceto Portella, Lina Maria Marin, Edson Crusca, Ed S. Krol, Walter L. Siqueira, Saulo Santesso Garrido
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2025-05-01
סדרה:	Microorganisms
נושאים:	histatin 5 P-113 proteolysis degradation saliva peptides
גישה מקוונת:	https://www.mdpi.com/2076-2607/13/5/1091
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