Synthesis and Study of the Structure–Activity Relationship of Antiproliferative <i>N</i>-Substituted Isosteviol-Based 1,3-Aminoalcohols

Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were prepared via stereoselective transformations. The acid-catalysed hydrolysis and rearrangement of natural stevioside produced isosteviol, which was transformed into the key intermediate methyl ester. In the next step,...

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Prif Awduron:	Dániel Ozsvár, Noémi Bózsity, István Zupkó, Zsolt Szakonyi
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2024-02-01
Cyfres:	Pharmaceuticals
Pynciau:	isosteviol diterpene chiral aminoalcohol antiproliferative SAR study
Mynediad Ar-lein:	https://www.mdpi.com/1424-8247/17/2/262
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!