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Salivary DNA methylation and pubertal development in adolescents

Abstract Individuals differ in when and how quickly they experience puberty, and these differences in pubertal development are associated with lifelong health and mortality. We conducted sex-specific epigenome-wide association analyses of salivary DNA-methylation (DNAm) samples from ~ 3500 adolescen...

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Hlavní autoři: Abby J. deSteiguer, Trey Smith, Joshua A. Goode, Yayouk E. Willems, Alicia M. Schowe, Darina Czamara, Bastian Mönkediek, Charlotte K. L. Pahnke, Andreas J. Forstner, Elisabeth B. Binder, Lisa Schneper, Daniel A. Notterman, Elliot M. Tucker-Drob, Laurel Raffington, Colter Mitchell, K. Paige Harden
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-10-01
Edice:Scientific Reports
Témata:
Puberty
Menarche
Aging
Epigenetics
DNA-methylation
On-line přístup:https://doi.org/10.1038/s41598-025-19588-1
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