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Development and Application of Immunoaffinity Column Purification and Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry for Determination of Domoic Acid in Shellfish

Domoic acid (DA) is a neurotoxin associated with amnesic shellfish poisoning (ASP). Though LC coupled to tandem mass spectrometry (LC-MS/MS) has become the preferred method for DA determination, traditional sample pretreatment is still labor-intensive. In this study, a simple, efficient and selectiv...

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Principais autores: Si Chen, Xiaojun Zhang, Zhongyong Yan, Yangyang Hu, Yibo Lu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2019-02-01
Series:Toxins
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Acceso en liña:https://www.mdpi.com/2072-6651/11/2/83
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