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2-Butoxytetrahydrofuran and Palmitic Acid from <i>Holothuria scabra</i> Enhance <i>C. elegans</i> Lifespan and Healthspan via DAF-16/FOXO and SKN-1/NRF2 Signaling Pathways

Extracts from a sea cucumber, <i>Holothuria scabra</i>, have been shown to exhibit various pharmacological properties including anti-oxidation, anti-aging, anti-cancer, and anti-neurodegeneration. Furthermore, certain purified compounds from <i>H. scabra</i> displayed neuroprotective effects against...

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Principais autores: Prapaporn Jattujan, Sirin Srisirirung, Warisra Watcharaporn, Kawita Chumphoochai, Pichnaree Kraokaew, Tanatcha Sanguanphun, Prachayaporn Prasertsuksri, Salinthip Thongdechsri, Prasert Sobhon, Krai Meemon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-11-01
coleção:Pharmaceuticals
Assuntos:
lifespan
oxidative stress
<i>Holothuria scabra</i>
<i>Caenorhabditis elegans</i>
DAF-16
SKN-1
Acesso em linha:https://www.mdpi.com/1424-8247/15/11/1374
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