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CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging

In the absence of transcription, gene expression required for oocyte maturation is regulated by translation of preexisting mRNAs. Here the authors show that a defective program of mRNA translation in oocyte is associated with maternal aging.

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Detalhes bibliográficos
Principais autores: Nozomi Takahashi, Federica Franciosi, Enrico Maria Daldello, Xuan G. Luong, Peter Althoff, Xiaotian Wang, Marco Conti
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2023-01-01
Colecção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-023-35994-3
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