Comparison of multiple genotyping methods for the identification of the cancer predisposing founder mutation p.R337H in TP53
Abstract Germline mutations in the TP53 gene are associated with Li-Fraumeni and Li-Fraumeni-Like Syndromes, characterized by increased predisposition to early-onset cancers. In Brazil, the prevalence of the TP53-p.R337H germline mutation is exceedingly high in the general population and in cancer-a...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Sociedade Brasileira de Genética
2016-06-01
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| Seri Bilgileri: | Genetics and Molecular Biology |
| Konular: | |
| Online Erişim: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572016000200203&tlng=en |
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