Curcumin Diglutaric Acid, a Prodrug of Curcumin Reduces Pain Hypersensitivity in Chronic Constriction Injury of Sciatic Nerve Induced-Neuropathy in Mice

The drug treatment for neuropathic pain remains a challenge due to poor efficacy and patient satisfaction. Curcumin has been reported to alleviate neuropathic pain, but its clinical application is hindered by its low solubility and poor oral bioavailability. Curcumin diglutaric acid (CurDG) is a cur...

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Hlavní autoři:	Thanchanok Limcharoen, Peththa Wadu Dasuni Wasana, Hasriadi, Chawanphat Muangnoi, Opa Vajragupta, Pornchai Rojsitthisak, Pasarapa Towiwat
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2020-08-01
Edice:	Pharmaceuticals
Témata:	neuropathic pain chronic constriction injury curcumin diglutaric acid mechanical allodynia thermal hyperalgesia
On-line přístup:	https://www.mdpi.com/1424-8247/13/9/212
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