Challenge of missing data in observational studies: investigating cross-sectional imputation methods for assessing disease activity in axial spondyloarthritis

Objectives We aimed to compare various methods for imputing disease activity in longitudinally collected observational data of patients with axial spondyloarthritis (axSpA).Methods We conducted a simulation study on data from 8583 axSpA patients from ten European registries. Disease activity was ass...

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Autori principali:	Bente Glintborg, Merete Lund Hetland, Tore K Kvien, Tor Olofsson, Brigitte Michelsen, Florenzo Iannone, Ziga Rotar, Catalin Codreanu, Mikkel Østergaard, Jakub Zavada, Olafur Palsson, Bjorn Gudbjornsson, Adrian Ciurea, Daniela Di Giuseppe, Ovidiu Rotariu, Stylianos Georgiadis, Ross MacDonald, Sella Aarrestad Provan, Vappu Rantalaiho, Diogo Almeida, Ritva Peltomaa, Louise Linde, L M Ørnbjerg, Johan K Wallman, Marion Pons, Anne G Loft, Katja Perdan Pirkmajer, Simon Rasmussen, Daniel Melim, Karin Lass
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMJ Publishing Group 2025-02-01
Serie:	RMD Open
Accesso online:	https://rmdopen.bmj.com/content/11/1/e004844.full
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