Nicotinamide Mononucleotide Administration Triggers Macrophages Reprogramming and Alleviates Inflammation During Sepsis Induced by Experimental Peritonitis

Peritonitis and subsequent sepsis lead to high morbidity and mortality in response to uncontrolled systemic inflammation primarily mediated by macrophages. Nicotinamide adenine dinucleotide (NAD+) is an important regulator of oxidative stress and immunoinflammatory responses. However, the effects of...

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Autors principals:	Cécile Cros, Marielle Margier, Hélène Cannelle, Julie Charmetant, Nicolas Hulo, Laurent Laganier, Alessia Grozio, Matthias Canault
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-06-01
Col·lecció:	Frontiers in Molecular Biosciences
Matèries:	sepsis peritonitis nicotinamide mononucleotide nicotinamide adenine dinucleotide monocyte macrophage
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.895028/full
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