Revisiting the Radiosynthesis of [¹⁸F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer’s Disease

[¹⁸F]FPEB is a positron emission tomography (PET) radiopharmaceutical used for imaging the abundance and distribution of mGluR5 in the central nervous system (CNS). Efficient radiolabeling of the aromatic ring of [¹⁸F]FPEB has been an ongoing challenge. Herein, five metal-free...

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Autori principali:	Cassis Varlow, Emily Murrell, Jason P. Holland, Alina Kassenbrock, Whitney Shannon, Steven H. Liang, Neil Vasdev, Nickeisha A. Stephenson
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-02-01
Serie:	Molecules
Soggetti:	[<sup>18</sup>f]fpeb mglur5 positron emission tomography (pet) iodonium-ylide alzheimer’s disease (ad)
Accesso online:	https://www.mdpi.com/1420-3049/25/4/982
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