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Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis

Abstract Clusterin (CLU) is a stress‐activated molecular chaperone that confers treatment resistance to taxanes when highly expressed. While CLU inhibition potentiates activity of taxanes and other anti‐cancer therapies in preclinical models, progression to treatment‐resistant disease still occurs i...

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Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Nader Al Nakouzi, Chris Kedong Wang, Eliana Beraldi, Wolfgang Jager, Susan Ettinger, Ladan Fazli, Lucia Nappi, Jennifer Bishop, Fan Zhang, Anne Chauchereau, Yohann Loriot, Martin Gleave
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Springer Nature 2016-05-01
Sraith:EMBO Molecular Medicine
Ábhair:
Rochtain ar líne:https://doi.org/10.15252/emmm.201506059
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