Hypertonic Saline Suppresses NADPH Oxidase-Dependent Neutrophil Extracellular Trap Formation and Promotes Apoptosis

Tonicity of saline (NaCl) is important in regulating cellular functions and homeostasis. Hypertonic saline is administered to treat many inflammatory diseases, including cystic fibrosis. Excess neutrophil extracellular trap (NET) formation, or NETosis, is associated with many pathological conditions...

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Bibliografiske detaljer

Principais autores:	Ajantha Nadesalingam, Jacky H. K. Chen, Armin Farahvash, Meraj A. Khan
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2018-03-01
Serier:	Frontiers in Immunology
Fag:	hypertonic saline NaCl neutrophil extracellular traps NOX2-dependent NETosis lipopolysaccharide-induced NETosis Gram-negative and -positive bacteria-induced NETosis
Online adgang:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00359/full
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