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Serious Hemorrhagic Complications After Successful Treatment of Hematopoietic Stem Cell Transplantation-Associated Thrombotic Microangiopathy With Defibrotide in Pediatric Patient With Myelodysplastic Syndrome

Background: Transplant-associated thrombotic microangiopathy (TAM) is a life-threatening complication of hematopoietic stem cell transplantation (HSCT). There is some evidence of endothelial injury playing a significant role in TAM development. The efficacy of defibrotide was demonstrated for prophy...

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Principais autores: Alexandra Laberko, Marina Aksenova, Irina Shipitsina, Igor Khamin, Anna Shcherbina, Dmitry Balashov, Alexei Maschan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
coleção:Frontiers in Pediatrics
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fped.2020.00155/full
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