Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness

Abstract Genetic variants account for approximately half the cases of congenital and early‐onset deafness. Methods and technologies for viral delivery of genes into the inner ear have evolved over the past decade to render gene therapy a viable and attractive approach for treatment. Variants in SYNE...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Shahar Taiber, Roie Cohen, Ofer Yizhar‐Barnea, David Sprinzak, Jeffrey R Holt, Karen B Avraham
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Springer Nature 2020-12-01
Цуврал:	EMBO Molecular Medicine
Нөхцлүүд:	deafness DFNB76 gene therapy Nesprin‐4 SYNE4
Онлайн хандалт:	https://doi.org/10.15252/emmm.202013259
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!