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Applying phylogenetic methods for species delimitation to distinguish B-cell clonal families

The adaptive immune system generates a diverse array of B-cell receptors through the processes of V(D)J recombination and somatic hypermutation. B-cell receptors that bind to an antigen will undergo clonal expansion, creating a Darwinian evolutionary dynamic within individuals. A key step in studyin...

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Bibliografiske detaljer
Principais autores: Katalin Voss, Katrina M. Kaur, Rituparna Banerjee, Felix Breden, Matt Pennell
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-12-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1505032/full
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