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Visualization and Analysis of the Dynamic Assembly of a Heterologous Lantibiotic Biosynthesis Complex in <named-content content-type="genus-species">Bacillus subtilis</named-content>

ABSTRACT A membrane-associated lanthipeptide synthetase complex, consisting of the dehydratase NisB, the cyclase NisC, and the ABC transporter NisT, has been described for nisin biosynthesis in the coccoid bacterium Lactococcus lactis. Here, we used advanced fluorescence microscopy to visualize the...

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Principais autores: Jingqi Chen, Auke J. van Heel, Oscar P. Kuipers
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021-08-01
Serier:mBio
Fag:
Bacillus subtilis
nisin
lantibiotic biosynthesis machinery
subcellular localization
assembly dynamics
fluorescence microscopy
Online adgang:https://journals.asm.org/doi/10.1128/mBio.01219-21
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