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ROS and Lipid Droplet accumulation induced by high glucose exposure in healthy colon and Colorectal Cancer Stem Cells

Lipid Droplets (LDs) are emerging as crucial players in colon cancer development and maintenance. Their expression has been associated with high tumorigenicity in Cancer Stem Cells (CSCs), so that they have been proposed as a new functional marker in Colorectal Cancer Stem Cells (CR-CSCs). They are...

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Principais autores: Luca Tirinato, Francesca Pagliari, Simone Di Franco, Elisa Sogne, Maria Grazia Marafioti, Jeanette Jansen, Andrea Falqui, Matilde Todaro, Patrizio Candeloro, Carlo Liberale, Joao Seco, Giorgio Stassi, Enzo Di Fabrizio
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2020-12-01
coleção:Genes and Diseases
Assuntos:
Cholesterol metabolism
Colorectal cancer stem cells
Fatty acid metabolism
High glucose
Lipid droplets
Oncogenes
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352304219300819
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