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Antibody Fc-chimerism and effector functions: When IgG takes advantage of IgA

Recent advances in the development of therapeutic antibodies (Abs) have greatly improved the treatment of otherwise drug-resistant cancers and autoimmune diseases. Antibody activities are mediated by both their Fab and the Fc. However, therapeutic Abs base their protective mechanisms on Fc-mediated...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Andréa Cottignies-Calamarte, Daniela Tudor, Morgane Bomsel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-02-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1037033/full
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