Dehydroepiandrosterone Cocrystals with Improved Solubility and Bioavailability

Dehydroepiandrosterone (DHEA) is an FDA-approved food supplement used as an assisted reproductive sex hormone. The bioavailability is severely limited by its poor solubility (23 µg/mL). Herein, we aimed to modulate its solubility through cocrystallization. Eight cocrystals of DHEA with pyrocatechol...

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Prif Awduron:	Yihua Jiang, Yinxiang Cheng, Mengyuan Xia, Bingrui Zhang, Qiaoce Ding, Liye Lu, Jian-Rong Wang, Xuefeng Mei
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2022-11-01
Cyfres:	Pharmaceutics
Pynciau:	DHEA cocrystallization crystal structure solubility bioavailability
Mynediad Ar-lein:	https://www.mdpi.com/1999-4923/14/11/2478
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!