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Cellular and matrix interactions during the development of T lymphocytes

The thymus contains an extensive extracellular matrix. Although thymocytes express integrins capable of binding to matrix molecules, the functional significance of the matrix for T cell development is uncertain. We have shown that the matrix is associated with thymic fibroblasts which are required f...

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Detalles Bibliográficos
Principais autores: J.J.T. Owen, D.E. McLoughlin, R.K. Suniara, E.J. Jenkinson
Formato: Artigo
Idioma:Inglês
Publicado: Associação Brasileira de Divulgação Científica 1999-05-01
Series:Brazilian Journal of Medical and Biological Research
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Acceso en liña:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000500008
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