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Alzheimer’s Disease and Age-Related Changes in the Cu Isotopic Composition of Blood Plasma and Brain Tissues of the APP<sup>NL-G-F</sup> Murine Model Revealed by Multi-Collector ICP-Mass Spectrometry

Alzheimer’s’ disease (AD) is characterized by the formation of β-amyloid (Aβ) plaques and neurofibrillary tangles of tau protein in the brain. Aβ plaques are formed by the cleavage of the β-amyloid precursor protein (APP). In addition to protein aggregations, the metabolism of the essential mineral...

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主要な著者: Kasper Hobin, Marta Costas-Rodríguez, Elien Van Wonterghem, Roosmarijn E. Vandenbroucke, Frank Vanhaecke
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2023-06-01
シリーズ:Biology
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オンライン・アクセス:https://www.mdpi.com/2079-7737/12/6/857
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