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Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance

Obesity-related inflammation of metabolic tissues, including visceral adipose tissue (VAT) and liver, are key factors in the development of insulin resistance (IR), though many of the contributing mechanisms remain unclear. We show that nucleic-acid-targeting pathways downstream of extracellular tra...

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Principais autores: Xavier S. Revelo, Magar Ghazarian, Melissa Hui Yen Chng, Helen Luck, Justin H. Kim, Kejing Zeng, Sally Y. Shi, Sue Tsai, Helena Lei, Justin Kenkel, Chih Long Liu, Stephanie Tangsombatvisit, Hubert Tsui, Corneliu Sima, Changting Xiao, Lei Shen, Xiaoying Li, Tianru Jin, Gary F. Lewis, Minna Woo, Paul J. Utz, Michael Glogauer, Edgar Engleman, Shawn Winer, Daniel A. Winer
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-07-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124716307641
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