Histone H3K9 and H4 Acetylations and Transcription Facilitate the Initial CENP-AHCP−3 Deposition and De Novo Centromere Establishment in Caenorhabditis elegans Artificial Chromosomes

Abstract Background The centromere is the specialized chromatin region that directs chromosome segregation. The kinetochore assembles on the centromere, attaching chromosomes to microtubules in mitosis. The centromere position is usually maintained through cell cycles and generations. However, new c...

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Hauptverfasser:	Jing Zhu, Kevin Chi Lok Cheng, Karen Wing Yee Yuen
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2018-04-01
Schriftenreihe:	Epigenetics & Chromatin
Schlagworte:	De novo centromeres Neocentromeres Centromere establishment Artificial chromosomes Epigenetics Chromatin environment
Online-Zugang:	http://link.springer.com/article/10.1186/s13072-018-0185-1
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