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Synergistic Anticancer Effects of Metformin and Doxorubicin in Ovarian Cancer Cells Through Dual Apoptotic Pathway Activation and Oxidative Stress Enhancement

This study aimed to evaluate the antiproliferative, apoptotic, and oxidative stress-inducing effects of the combination of metformin and doxorubicin (adriamycin) in OVCAR3 and SKOV3 ovarian cancer cell lines and to investigate the potential synergistic interactions between the two agents. Cell viabi...

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Autores principales: Senem Alkan Akalın, Yasemin Afşin, Veysel Toprak, İlhan Özdemir, Mehmet Cudi Tuncer, Şamil Öztürk
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2025-12-01
Colección:Biology
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Acceso en línea:https://www.mdpi.com/2079-7737/14/12/1749
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