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Effect of adeno-associated virus (AAV)-mediated overexpression of PEPCK-M (Pck2) on Clenbuterol-induced muscle growth.

We previously identified PEPCK-M (encoded by the Pck2 gene) to be highly up-regulated in skeletal muscle of pigs treated with Ractopamine, an anabolic beta-adrenergic receptor agonist. To determine whether PEPCK-M had a causative role in modulating the skeletal muscle growth response to Ractopamine,...

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Principais autores: David M Loczenski-Brown, Sarah Jones, Jeni Luckett, Zoe Daniel, Madelaine C Brearley, Francis J P Ebling, Tim Parr, John M Brameld
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2019-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0218970
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