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Decoding Leukemic Stem Cells in AML: From Identification to Targeted Eradication

Acute myeloid leukemia (AML) continues to pose significant therapeutic challenges, with high relapse rates driven largely by leukemic stem cells (LSCs), a rare, therapy-resistant population with self-renewal capacity, niche adaptation, and the ability to re-initiate disease. In this state-of-the-art...

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Principais autores: Elisavet Apostolidou, Vasileios Georgoulis, Dimitrios Leonardos, Leonidas Benetatos, Eleni Kapsali, Eleftheria Hatzimichael
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-01-01
Serier:Diseases
Fag:
acute myeloid leukemia
leukemic stem cells
immunophenotype
targeted treatment
Online adgang:https://www.mdpi.com/2079-9721/14/2/50
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