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Antigen cross-priming of cell-associated proteins is enhanced by macroautophagy within the antigen donor cell

Phagocytosis of dying cells constitutes an importance mechanism of antigen capture for the cross-priming of CD8+ T cells. This process has been shown to be critical for achieving tumor and viral immunity. While most studies have focused on the mechanisms inherent in the dendritic cell that account f...

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Detalles Bibliográficos
Principais autores: Matthew eAlbert, Pierre-Emmanuel eJoubert
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Immunology
Assuntos:
Acceso en liña:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00061/full
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