Concentrations of Co-Administered Meropenem and Vancomycin in Spinal Tissues Relevant for the Treatment of Pyogenic Spondylodiscitis—An Experimental Microdialysis Study

Co-administration of meropenem and vancomycin has been suggested as a systemic empirical antibiotic treatment of pyogenic spondylodiscitis. The aim of this study was, in an experimental porcine model, to evaluate the percentage of an 8-h dosing interval of co-administered meropenem and vancomycin co...

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Hauptverfasser:	Josefine Slater, Maiken Stilling, Pelle Hanberg, Sofus Vittrup, Martin Bruun Knudsen, Sara Kousgaard Tøstesen, Josephine Olsen Kipp, Mats Bue
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-05-01
Schriftenreihe:	Antibiotics
Schlagworte:	microdialysis meropenem vancomycin spondylodiscitis target site spinal tissues
Online-Zugang:	https://www.mdpi.com/2079-6382/12/5/907
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